CAUSES OF RECIPIENT BLOOD GROUP ANTIGEN POSITIVITY AFTER ENGRAFTMENT AFTER MAJOR/MINOR AND MINOR ABO MISMATCH IN CORD BLOOD TRANSPLANTATION
نویسندگان
چکیده
منابع مشابه
ABO blood group antigens on human plasma von Willebrand factor after ABO-mismatched bone marrow transplantation.
von Willebrand factor (vWF) is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. ABO blood group antigens are covalently associated with asparagine-linked sugar chains of plasma vWF. The effect of ABO-mismatched bone marrow transplantation (BMT) or blood stem cell transplantation (BSCT) on the expres...
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چکیده ندارد.
15 صفحه اولEnforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation.
Delayed engraftment is a major limitation of cord blood transplantation (CBT), due in part to a defect in the cord blood (CB) cells' ability to home to the bone marrow. Because this defect appears related to low levels of fucosylation of cell surface molecules that are responsible for binding to P- and E-selectins constitutively expressed by the marrow microvasculature, and thus for marrow homi...
متن کاملDelayed massive immune hemolysis mediated by minor ABO incompatibility after allogeneic peripheral blood progenitor cell transplantation.
BACKGROUND Bone marrow transplantation with minor ABO incompatibility may be followed by moderate delayed hemolysis of the recipient's red cells by donor-derived ABO antibodies. This reaction may be more severe after transplantation of peripheral blood progenitor cells (PBPCs). CASE REPORT A 16-year-old boy underwent an allogeneic PBPC transplant from his HLA-mismatched mother as treatment fo...
متن کاملEngraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen.
Umbilical cord blood transplant recipients are exposed to an increased risk of graft failure, a complication leading to a higher rate of transplant-related mortality. The decision and timing to offer a second transplant after graft failure is challenging. With the aim of addressing this issue, we analyzed engraftment kinetics and outcomes of 1268 patients (73% children) with acute leukemia (64%...
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ژورنال
عنوان ژورنال: Japanese Journal of Transfusion and Cell Therapy
سال: 2020
ISSN: 1881-3011,1883-0625
DOI: 10.3925/jjtc.66.718